The Mississippi House passed a bill banning transgender athletes from competing in girls' and women's sports by an 81-28 vote on Wednesday.
The ban will apply to state schools and universities and will require "any public school and university that is a member of the Mississippi High School Activities Association and NCAA, among other associations, to designate their athletic teams as male, female or co-ed and restrict athletes assigned male at birth from joining female teams."
"If we do not move to protect female sports from biological males who have an unfair physiological advantage, we will eventually no longer have female sports," said Angela Hill, a Mississippi Republican state senator and sponsor of the bill.
However, Human Rights Campaign President Alphonso David believes the state is on the "wrong side of history."
"Like all girls, transgender girls just want to play and be part of a team with their friends," said David. "History will not look kindly on this moment in Mississippi."
The bill, known as the Mississippi Fairness Act, will now be sent on to Republican Gov. Tate Reeves, who is expected to sign it.